The glucostator is a fully automated glucose metabolism measurement and control system that allows the user to accurately monitor the intravenous blood sugar level over a longer period of time. Even in times when no blood glucose controls occur, the BZ level of the patient patient is kept at the desired level. The stored data can be used to easily detect insulin and glucose requirements, e.g. over 24 hours. Without constant personnel effort, the user receives all the relevant data, which is important for glucose metabolism during the monitoring phase.
The closed loop system for controlling blood glucose levels for science – diagnostics – and therapy.
BUY OR RENT
Thanks to the extensive medical approval, the glucostator is now available worldwide directly for purchase or rent for your individual period. We are always in a position to offer individual solutions. In the early days, we will install the glucostator on site and implement a competent and detailed product training with you. After that, we will, of course, continue to be available for all support. We also receive annual maintenance of the entire system along an all-round carefree package. Just talk to us!
The glucostator uses the principle of continuous blood glucose measurement and offers timely feedback control based on this. The patient patient is removed from the patient patient via a special catheter system during use of the smallest amounts of blood (1 ml/h). After processing and mixing with a buffer solution, the blood-/buffer mixture is fed to a highly sensitive glucose sensor. A blood glucose level of more than one minute is calculated from 120 individual measurements and displayed numerically. Blood glucose levels are stored in a file in the glucostator and graphically represented as a blood sugar curve. In the functional modes with blood sugar-controlled feedback, the necessary infusion rates for insulin and glucose therapy are calculated from the blood glucose levels determined, in conjunction with the program parameters set by the user, and Venously infused. The insulin and glucose concentration of the infusions can be freely chosen. Upon completion of an application, a file is available for further evaluation in which all important information is stored over the entire period of time: Date, time, BZ value, current total insulin rate, current total glucoserate total quantity, User note.
However, the area of application of the glucostone statue is not only to be seen in the scientific environment. Due to its compact design, it is also a unique tool for clinical questions: The measurement of intravenous blood glucose, including the regulation of insulin and dextrosis intake, is fully automatic. You have the option of influencing blood sugar-controlled feedback by entering metabolism-relevant parameters. For the intensively treated patient, for whom a control of blood glucose levels over a longer period of time is an important metabolic size, the glucostator can assist you in the therapy.
BLOOD SUGAR ADJUSTMENT IN INTENSIVE PATIENTS
What has been classified as a very urgent topic in endocrinological circles for many years can be demonstrated by the interesting and clinical-scientifically very valuable study of Van den Berghe, et al: Blood sugar levels are a hugely important parameter. The study showed that intensive insulin therapy significantly reduced the mortality of treated patients. And not only in manifest diabetes patients, but in principle in all intensive care patients. It has thus been proven that a tight euglycemic attitude can significantly improve morbidity.
In everyday clinical life in intensive care, it is not always easy, for example, to react to short-term physiological changes in blood sugar levels or to record an acute blood sugar derailment in a timely manner in the event of artificially obtained vital function, which does not Is rarely triggered by switching effects with other medications.
In intensely treated patients, many vital functions are monitored online.
So why not also the vital function blood sugar?
In order to carry out the monitoring of intravenous blood sugar automatically and online, the intensive care unit is currently suitable, as various intravenous approaches are laid in intensively treated patients anyway.
The glucostator works on the basis of the former BIOSTATORs (Ulm University) and consists essentially of 5 main groups.
- Analyser with analyzer pump and sensor chamber
- Electrochemical sensor
- Insulin infusion pump
- Glucose infusion pump
The Patient/Proband is continuously removed from the Patient/Proband by a patented catheter system (mtbDLC) of the smallest amounts of blood (about 1ml venous thoroughbred/hour). Blood collection takes over a miniaturized analysis pump. To avoid clotting during prolonged examination periods, the “double umber catheter” (DLC) is constantly rinsed with a salt/heparin mixture. This mixed fluid is sterile. It is not fed to the Patient/Proband, but is pumped back from the DLC due to a higher outflow rate. Accidental heparination of the Patient/Proband is therefore excluded.
The removed thoroughbred/heparin mixture is mixed with a buffer concentrate in an external mixing chamber and fed to an enzymatic sensor chamber, which continuously measures blood sugar levels. The measurement signal is processed and modified in the analyser. The digital signal obtained in this way is processed in the computer by the chosen algorithm. The removed blood is no longer fed to the Patient, but is collected in a collection container for disposal. The hoses and materials associated with the patient are manufactured and sterilized in accordance with the legal regulations.
All try-relevant limits are entered by the user at the beginning of the experiment. They control commercially available insulin – and glucose – infusion pump in conjunction with the fixed algorithms. These infuse the amount of insulin and/or glucose to the patient patient patient’s patient patient via an additional separate venous access. This circuit ensures that glucose levels entered by the operator are set and kept stable, regardless of other influences relevant to glucose metabolism. On the screen, the continuous blood glucose value, the insulin and dextroserates as well as the amount of insulin and dextrose administered are displayed graphically and proportionally. Glucostator’s program parameters include additional alarm constants and safety limits that characterize a physiologically unusual test history and signal it through alerts.
HERE THE GLUCOSTATOR IS USED
University Hospital Tübingen (Germany)
Wockhardt Hospital (India)
University of Berlin (Germany)
University of Athens (Greece)
University of Montreal (Canada)
University of Kiel (Germany)
University of Marburg (Germany)
University of Mainz (Germany)
Altenburg Hospital (Germany)
Maastricht University (Netherlands)
University of Graz (Austria)
Use and cost-effectiveness
Due to its tripod structure and the resulting slim dimensions, the glucostator fits next to every bed of sickness, even in the intensive area, or surgery. The glucostator is economical to operate due to low consumption costs and inexpensive reagents.
Continuous measurement with the glucostator not only offers savings in consumables. The cost-intensive personnel use that arises from individual measurements can also be reduced to a minimum.
Alarm features and security devices
The glucostator has all the alarm functions that become dangerous for metabolism. The readings are constantly checked: For example, with each unphysiological change in the measured glucose values, or when a fixed limit is exceeded, the alarm is given. This is indicated by a flashing warning message on the display and an acoustic alarm signal. The controlled infusion pumps are also switched off immediately.